Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F11 | P03951 | 20/20 | 0.63 |
| ▸ | KLKB1 | P03952 | 15/20 | 0.63 |
| ▸ | F10 | P00742 | 4/20 | 0.55 |
| ▸ | PLG | P00747 | 4/20 | 0.55 |
| ▸ | PLAT | P00750 | 3/20 | 0.55 |
| ▸ | PROC | P04070 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.55 |
| ▸ | F9 | P00740 | 1/20 | 0.55 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.55 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.55 |
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3662457 | 1.00 | F11 (0.63) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3668610 | 0.93 | F11 (0.61) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3668623 | 0.93 | F11 (0.61) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3664217 | 0.91 | F11 (0.76) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3664533 | 0.91 | F11 (0.66) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3668471 | 0.90 | F11 (0.60) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3668473 | 0.90 | F11 (0.60) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3662754 | 0.88 | F11 (0.63) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3662762 | 0.88 | F11 (0.63) | F11KLKB1F10PLGPLAT | |
| SCHEMBL3663390 | 0.88 | F11 (0.68) | F11KLKB1F10PLGPLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2152664-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | Brystol-Myers Squibb Company (US) | 2010-02-17 | — | — | EP | disclosed |
| WO-2008157162-A1 | DIPEPTIDE ANALOGS AS COAGULATION FACTOR INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |