SCHEMBL3662893

SCHEMBL3662893

CC#CCOc1cccc(N(C)C(=O)c2ccc3ncccc3c2)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.42
HTT P42858 1/20 0.42
PLK1 P53350 1/20 0.40
LMNA P02545 2/20 0.39
ALDH1A1 P00352 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
DOT1L Q8TEK3 1/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
NOTUM Q6P988 1/20 0.38
NPC1 O15118 4/20 0.37
RAB9A P51151 3/20 0.37
POLB P06746 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
RECQL P46063 2/20 0.35
HPGD P15428 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
CSF1R P07333 1/20 0.35
BRAF P15056 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3659703 0.92 ALOX15 (0.42) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3662142 0.91 ALOX15 (0.41) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3660226 0.90 ALOX15 (0.40) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3656299 0.90 ALOX15 (0.40) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3660238 0.90 ALOX15 (0.43) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3660738 0.89 ALOX15 (0.40) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3663834 0.88 ALOX15 (0.39) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3657849 0.88 ALOX15 (0.39) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3657878 0.88 ALOX15 (0.39) ALOX15HTTPLK1LMNAALDH1A1
SCHEMBL3275312 0.87 ALOX15 (0.46) ALOX15HTTPLK1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2215062-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME Sumitomo Chemical Company, Limited (JP) 2010-08-11 EP disclosed
WO-2009069792-A1 AMIDE COMPOUNDS AND PLANT DISEASE CONTROLLING METHOD USING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-06-04 WO disclosed