Isothiazole

Isothiazole

SCHEMBL3663008

C1=CC2=CCC=CN2C=C1.c1cnsc1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6174797 0.80
SCHEMBL27831840 0.79
SCHEMBL5853356 0.67
Isothiazole SCHEMBL5679 0.62
Isothiazole SCHEMBL642842 0.62
Isothiazole SCHEMBL28850780 0.61
Isothiazole SCHEMBL27427269 0.60
Isothiazole SCHEMBL28981301 0.60
Isothiazole SCHEMBL9391996 0.60
Isothiazole SCHEMBL30450994 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2242498-A2 SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS Tyratech, Inc. (US) 2010-10-27 EP disclosed
WO-2009086471-A2 SYNERGISTIC ANTIPARASITIC COMPOSITIONS AND SCREENING METHODS TYRATECH, INC. (US) 2009-07-09 WO disclosed