Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366302 | 0.94 | ALDH1A1 (0.47) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL366412 | 0.94 | ALDH1A1 (0.49) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL365411 | 0.93 | ALDH1A1 (0.53) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL367008 | 0.93 | ALDH1A1 (0.48) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL365388 | 0.92 | ALDH1A1 (0.49) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL364202 | 0.92 | ALDH1A1 (0.45) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL365860 | 0.92 | ALDH1A1 (0.45) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL365040 | 0.91 | ALDH1A1 (0.48) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL364892 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TDP1PHLPP2RAD52POLB | |
| SCHEMBL365858 | 0.90 | ALDH1A1 (0.47) | ALDH1A1TDP1PHLPP2RAD52POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |