Dinitrophenylene

Dinitrophenylene

SCHEMBL36632

O=[N+]([O-])c1cccc([N+](=O)[O-])c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 1.00
LMNA P02545 2/20 1.00
CES2 O00748 1/20 0.71
CES1 P23141 1/20 0.71
ALDH1A1 P00352 6/20 0.70
ACHE P22303 1/20 0.70
TDP1 Q9NUW8 1/20 0.70
ALOX15 P16050 1/20 0.70
HSP90AA1 P07900 1/20 0.67
GAA P10253 1/20 0.64
HTT P42858 1/20 0.64
KMT2A Q03164 1/20 0.64
TP53 P04637 1/20 0.61
NFE2L2 Q16236 1/20 0.59
CA2 P00918 1/20 0.59
CA5A P35218 1/20 0.59
FBP1 P09467 1/20 0.57
VCP P55072 1/20 0.57
CYP19A1 P11511 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dinitrophenylene SCHEMBL29291896 1.00 TSHR (1.00) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL9733861 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL30600045 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL27759628 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL2997371 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL29143070 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL9733868 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL29834109 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL11661349 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1
Dinitrophenylene SCHEMBL27527476 0.97 TSHR (0.94) TSHRLMNACES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 7586 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121064050-B Preparation method of 2', 4-dichloro-2-aminodiphenyl ether Yantai Taihe New Material Polymer New Material Research Institute Co.,Ltd. (CN) 2026-05-26 CN claimed
CN-122079787-A Preparation method of p-phenylenediamine anti-aging agent intermediate 2, 4-diaminodiphenylamine 2026-05-26 CN claimed
EP-4727911-A2 FLUORINATION METHODS, REAGENTS, FLUORINATED COMPOSITIONS, AND METHODS OF MANUFACTURE FLUOROK LIMITED (GB) 2026-04-22 EP claimed
US-12494509-B2 Non-aqueous ammonia electrolytes for lithium anode based primary and reserve batteries MAXPOWER, INC. (US) 2025-12-09 US claimed
CN-117069594-B Synthesis method of 1, 3-cyclohexanediamine 江苏清泉化学股份有限公司 2025-06-13 CN claimed
CN-116285852-B Adhesive and preparation method thereof 马鞍山海鹰新材料有限公司 2025-06-03 CN claimed
CN-119972147-A Calcium carbonate/carbon composite carrier supported ruthenium catalyst, preparation method and application 郑州大学 2025-05-13 CN claimed
CN-119528747-B Preparation method of 3,4' -diaminodiphenyl ether 烟台泰和新材高分子新材料研究院有限公司 2025-05-13 CN claimed
CN-119823165-A Dinaphthosilole compound, synthesis method and application thereof in fluorescence detection of nitroaromatic ring compound 亳州学院 2025-04-15 CN claimed
CN-119715865-A Method for measuring target organic matters in waste acid 四川北方红光特种化工有限公司 2025-03-28 CN claimed
US-4225648-A PROTECTIVE COATING OF POLYMER CONTAINING LEWIS ACID RICOH COMPANY, LTD. (JP) 1980-09-30 US claimed
EP-0010451-A1 Process for the delignification of lignocellulosic material and products thereof C.I.L. Inc. (CA) 1980-04-30 EP claimed
US-4157445-A Method for the preparation of quinoline and aniline compounds UNION CARBIDE CORPORATION (US) 1979-06-05 US claimed
US-4103057-A SYNDIOTACTIC POLY(1,2-)BUTADIENE NIPPON PAINT COMPANY (JP) 1978-07-25 US claimed
US-4082538-A HERBICIDES FOR MONOCOTYLEDONS AND DICOTYLEDONS ROHM AND HAAS COMPANY (US) 1978-04-04 US claimed
US-4056523-A SULFONAMIDO SUBSTITUTED HOECHST AKTIENGESELLSCHAFT (DT) 1977-11-01 US claimed
US-4036864-A Chemical process RESEARCH INSTITUTE FOR MEDICINE AND CHEMISTRY INC. (US) 1977-07-19 US claimed
US-4036680-A Delignification of lignocellulosic material with a soda pulping liquor containing a Diels Alder adduct of benzoquinone or naphthoquinone in admixture with a nitro aromatic compound CANADIAN INDUSTRIES, LTD. (CA) 1977-07-19 US claimed
US-3998894-A DIMERIZATION AND CYCLIZATION OF A STYRENE AND A HAL GENO-STYRENE BASF AKTIENGESELLSCHAFT (DT) 1976-12-21 US claimed
US-3963676-A TETRAOXANE, TETRANITROMETHANE, MONO, DI, OR TRI-NITROBENZENES, DIPHENYL PICRYL HYDRAZINE PROMOTERS JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1976-06-15 US claimed