Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.46 |
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | RXRG | P48443 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | APAF1 | O14727 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364182 | 0.91 | MAOB (0.46) | MAOBKMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL364482 | 0.90 | KDM4E (0.48) | PTGESKMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL366971 | 0.90 | MAPT (0.48) | KMT2AMAPTGAASMN1; SMN2MEN1 | |
| SCHEMBL366360 | 0.87 | FFAR1 (0.47) | MAOBMAOAKMT2AMAPTGAA | |
| SCHEMBL366974 | 0.87 | MAOB (0.49) | MAOBKMT2AMAPTMEN1KDM4E | |
| SCHEMBL365497 | 0.86 | MAOB (0.50) | MAOBMAOAKMT2AMAPTMEN1 | |
| SCHEMBL366702 | 0.86 | MAOB (0.48) | MAOBKMT2AMAPTGAAMEN1 | |
| SCHEMBL364702 | 0.86 | KDM4E (0.45) | ALOX5KMT2AMAPTCYP1A2GAA | |
| SCHEMBL364784 | 0.85 | KDM4E (0.47) | MAOBKMT2AMAPTGAASMN1; SMN2 | |
| SCHEMBL366339 | 0.85 | KMT2A (0.64) | MAOBMAOAALOX5KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |