Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL367034 | 0.90 | ELANE (0.48) | MAOBELANEALKBH1KDM4EMAPT | |
| SCHEMBL364182 | 0.88 | MAOB (0.46) | FFAR1MAOBELANEKDM4EMAPT | |
| SCHEMBL364482 | 0.87 | KDM4E (0.48) | ELANEKDM4EMAPTMEN1APAF1 | |
| SCHEMBL366340 | 0.87 | MAOB (0.49) | FFAR1MAOBELANEKDM4EMAPT | |
| SCHEMBL366359 | 0.86 | KMT2A (0.60) | FFAR1FFAR4MAOBALKBH1GRM5 | |
| SCHEMBL366971 | 0.86 | MAPT (0.48) | KDM4EMAPTMEN1APAF1ALDH1A1 | |
| SCHEMBL366974 | 0.83 | MAOB (0.49) | FFAR1FFAR4MAOBKDM4EMAPT | |
| SCHEMBL365497 | 0.83 | MAOB (0.50) | FFAR1MAOBELANEKDM4EMAPT | |
| SCHEMBL366702 | 0.83 | MAOB (0.48) | MAOBELANEKDM4EMAPTMEN1 | |
| SCHEMBL364784 | 0.82 | KDM4E (0.47) | MAOBELANEKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |