SCHEMBL3663493

SCHEMBL3663493

N#CC(CCc1ccccc1)C(=O)O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CTSC P53634 1/20 0.48
CNR2 P34972 1/20 0.45
TSHR P16473 1/20 0.45
KEAP1 Q14145 1/20 0.44
ANPEP P15144 2/20 0.43
ERAP1 Q9NZ08 2/20 0.43
ERAP2 Q6P179 1/20 0.43
MME P08473 1/20 0.43
PPARG P37231 1/20 0.43
PPARA Q07869 1/20 0.43
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
KMT2A Q03164 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HPGD P15428 1/20 0.42
CYP1A2 P05177 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11827966 0.90 MMP12 (0.54) TSHRMMEHTT
SCHEMBL10420113 0.89 GRIK1 (0.50) CTSCPPARGPPARASMN1; SMN2
SCHEMBL4397838 0.87 TSHR (0.45) CTSCTSHRMEN1HTTKMT2A
SCHEMBL10419286 0.86 MAPT (0.50) SMN1; SMN2
SCHEMBL4397845 0.86 MAPT (0.50) SMN1; SMN2
SCHEMBL28747136 0.84 PPARG (0.47) CTSCPPARGPPARA
SCHEMBL4695604 0.83 CTSC (0.50) CTSCCNR2TSHRMEN1HTT
SCHEMBL4837691 0.82 CTSC (0.49) CTSCCNR2TSHRANPEPMEN1
SCHEMBL16672942 0.81 ERAP1 (0.46) CNR2TSHRKEAP1ANPEPERAP1
SCHEMBL1344165 0.81 CYP1A2 (0.55) CTSCMMECYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3956297-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-09-04 EP claimed
EP-3956293-B1 PROCESS FOR PREPARING CYANOACETATES HENKEL AG & CO KGAA (DE) 2024-08-07 EP claimed
CN-115151527-A Process for the preparation of cyanoacetic esters 汉高股份有限及两合公司 2022-10-04 CN claimed
CN-113710647-A Process for preparing cyanoacetic acid esters 汉高知识产权控股有限责任公司 2021-11-26 CN claimed
CN-113692400-A Process for preparing cyanoacetic acid esters 汉高知识产权控股有限责任公司 2021-11-23 CN claimed
US-20250304529-A1 BIOBASED CYANOACRYLATE COMPOUND BOSTIK SA (FR) 2025-10-02 US disclosed
EP-4532465-A1 BIOBASED CYANOACRYLATE COMPOUND Bostik SA (FR) 2025-04-09 EP disclosed
WO-2023232948-A1 BIOBASED CYANOACRYLATE COMPOUND BOSTIK SA (FR) 2023-12-07 WO disclosed
EP-4286369-A1 BIOBASED CYANOACRYLATE COMPOUND Bostik SA (FR) 2023-12-06 EP disclosed
CN-115151527-A Process for the preparation of cyanoacetic esters 汉高股份有限及两合公司 2022-10-04 CN disclosed
CN-110114337-A The method for preparing electron deficient olefins 汉高知识产权控股有限责任公司 2019-08-09 CN disclosed
CN-110099894-A The method for preparing electron deficient olefins precursor 汉高知识产权控股有限责任公司 2019-08-06 CN disclosed
EP-2527350-B1 Method for preparing phosphine butadiene ligands, complexes thereof with copper and the use of same in catalysis CENTRE NAT RECH SCIENT (FR) 2015-06-03 EP disclosed
EP-2147004-A2 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS Centre National De La Recherche Scientifique-CNRS (FR) 2010-01-27 EP disclosed
WO-2008129407-A2 METHOD FOR THE PREPARATION OF PHOSPHINE BUTADIENE LIGANDS, COMPLEXES THEREOF WITH COPPER AND USE THEREOF IN CATALYSIS CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) 2008-10-30 WO disclosed
EP-0787116-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE Akzo Nobel N.V. (NL) 1997-08-06 EP disclosed
WO-1996011894-A1 PROCESS FOR SEPARATING ENANTIOMERS FROM A RACEMIC MIXTURE AKZO NOBEL N.V. (NL) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304529-A1 BIOBASED CYANOACRYLATE COMPOUND BAP1, CBR1, CBR3 CTSC 4411/4885CNR2 1982/4885TSHR 4765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.