Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 19/20 | 0.60 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3665495 | 1.00 | CYP19A1 (0.60) | CYP19A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1651377 | 0.87 | CYP19A1 (0.64) | CYP19A1 | |
| SCHEMBL3663524 | 0.87 | CYP19A1 (0.64) | CYP19A1 | |
| SCHEMBL10920543 | 0.86 | CYP19A1 (0.60) | CYP19A1 | |
| SCHEMBL1331805 | 0.85 | CYP19A1 (0.59) | CYP19A1 | |
| SCHEMBL29288697 | 0.85 | CYP19A1 (0.58) | CYP19A1 | |
| SCHEMBL4298015 | 0.84 | CYP19A1 (0.69) | CYP19A1 | |
| SCHEMBL7596559 | 0.84 | PSEN1 (0.63) | CYP19A1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL29524618 | 0.83 | CYP19A1 (0.59) | CYP19A1 | |
| SCHEMBL28278507 | 0.83 | CYP19A1 (0.67) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2238149-A2 | 19-NOR-STEROID DERIVATIVES WITH A 15 ,16 -METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-10-13 | — | — | EP | claimed |
| WO-2009083272-A2 | 19-NOR-STEROID DERIVATIVES WITH A 15α,16α-METHYLENE GROUP AND A SATURATED 17,17-SPIROLACTONE RING, USE THEREOF, AND MEDICAMENTS CONTAINING SAID DERIVATIVES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-09 | — | — | WO | claimed |