Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 7/20 | 0.39 |
| ▸ | CA2 | P00918 | 7/20 | 0.39 |
| ▸ | CA12 | O43570 | 5/20 | 0.39 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | LATS1 | O95835 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955341 | 0.83 | MAOA (0.46) | MAOAMAOBCYP3A4CSNK2A2CSNK2A1 | |
| SCHEMBL6953013 | 0.83 | MAOA (0.46) | MAOAMAOBCYP3A4CSNK2A2CSNK2A1 | |
| SCHEMBL809997 | 0.80 | PLG (0.33) | — | |
| SCHEMBL810674 | 0.80 | PLG (0.33) | — | |
| SCHEMBL17074729 | 0.77 | CA12 (0.33) | MAOAMAOBTDP1CA1CA2 | |
| SCHEMBL6949199 | 0.76 | IKBKB (0.46) | MAOAMAOBCYP3A4CSNK2A2CSNK2A1 | |
| SCHEMBL810259 | 0.76 | IKBKB (0.46) | MAOAMAOBCYP3A4CSNK2A2CSNK2A1 | |
| Hydrochloric Acid SCHEMBL3666361 | 0.76 | MAOA (0.32) | MAOAMAOBCA1CA2CA12 | |
| SCHEMBL7070178 | 0.74 | CYP3A4 (0.44) | MAOAMAOBCYP3A4CSNK2A2CSNK2A1 | |
| SCHEMBL4420719 | 0.70 | CYP3A4 (0.44) | CYP3A4CSNK2A2CSNK2A1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2197443-A2 | COMPOSITIONS AND METHODS FOR EFFECTING NAD+ LEVELS USING A NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE INHIBITOR | Gemin X Pharmaceuticals Canada Inc. (CA) | 2010-06-23 | — | — | EP | claimed |
| WO-2009072004-A2 | COMPOSITIONS AND METHODS FOR EFFECTING NAD+ LEVELS USING A NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE INHIBITOR | GEMIN X PHARMACEUTICALS CANADA, INC. (US) | 2009-06-11 | — | — | WO | claimed |
| EP-2197443-A2 | COMPOSITIONS AND METHODS FOR EFFECTING NAD+ LEVELS USING A NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE INHIBITOR | Gemin X Pharmaceuticals Canada Inc. (CA) | 2010-06-23 | — | — | EP | disclosed |
| WO-2009072004-A2 | COMPOSITIONS AND METHODS FOR EFFECTING NAD+ LEVELS USING A NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE INHIBITOR | GEMIN X PHARMACEUTICALS CANADA, INC. (US) | 2009-06-11 | — | — | WO | disclosed |