Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.69 |
| ▸ | CA9 | Q16790 | 10/20 | 0.69 |
| ▸ | CA4 | P22748 | 7/20 | 0.69 |
| ▸ | CA2 | P00918 | 6/20 | 0.69 |
| ▸ | CA3 | P07451 | 6/20 | 0.69 |
| ▸ | CA5A | P35218 | 6/20 | 0.69 |
| ▸ | CA7 | P43166 | 6/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.69 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.69 |
| ▸ | CA1 | P00915 | 6/20 | 0.69 |
| ▸ | CA6 | P23280 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2978737 | 0.87 | CA12 (0.62) | CA12CA9CA4CA2CA3 | |
| SCHEMBL31741273 | 0.81 | CA12 (0.69) | CA12CA9CA4CA2CA3 | |
| SCHEMBL10350668 | 0.81 | CA12 (1.00) | CA12CA9CA4CA2CA3 | |
| SCHEMBL8750141 | 0.81 | CA12 (0.69) | CA12CA9CA4CA2CA3 | |
| SCHEMBL28776384 | 0.81 | CA12 (1.00) | CA12CA9CA4CA2CA3 | |
| SCHEMBL4926628 | 0.80 | CA12 (0.67) | CA12CA9CA4CA2CA3 | |
| SCHEMBL30843838 | 0.79 | CA12 (0.75) | CA12CA9CA4CA2CA3 | |
| SCHEMBL21657215 | 0.79 | CA12 (0.65) | CA12CA9CA4CA2CA3 | |
| SCHEMBL4927952 | 0.79 | CA12 (0.75) | CA12CA9CA4CA2CA3 | |
| SCHEMBL4927828 | 0.77 | CA12 (0.68) | CA12CA9CA4CA2CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119176798-A | Dihydropyrimidinone-coumarin derivative and preparation method thereof | 宜春学院 | 2024-12-24 | — | — | CN | claimed |
| CN-117866620-A | Cucurbituril [7] -cyclodextrin cascade assembled supermolecule system for specifically detecting trivalent gold and preparation method thereof | 曲阜师范大学 | 2024-04-12 | — | — | CN | claimed |
| CN-119060024-B | Aryl benzyl ether compound with affinity with monoamine oxidase B and application thereof | BEIJING NORMAL UNIVERSITY (CN) | 2026-05-26 | — | — | CN | disclosed |
| CN-119707900-A | Coumarin hydrazone derivatives with antioxidant activity and application thereof | 常州大学 | 2025-03-28 | — | — | CN | disclosed |
| CN-119176798-A | Dihydropyrimidinone-coumarin derivative and preparation method thereof | 宜春学院 | 2024-12-24 | — | — | CN | disclosed |
| CN-119060024-A | Aryl benzyl ether compound with affinity with monoamine oxidase B and application thereof | 北京师范大学 | 2024-12-03 | — | — | CN | disclosed |
| CN-118852077-A | Coumarin derivatives with breast cancer resisting activity and application thereof | 常州大学 | 2024-10-29 | — | — | CN | disclosed |
| CN-115894461-B | Novel coumarin-containing azole derivative, and preparation method and application thereof | 沈阳药科大学 | 2024-01-23 | — | — | CN | disclosed |
| CN-116948631-A | Macrocyclic mediated photoinduced emission enhanced high reversible supermolecule optical switch system, preparation and application in targeted cell imaging and anti-counterfeiting | 曲阜师范大学 | 2023-10-27 | — | — | CN | disclosed |
| CN-115894461-A | Novel coumarin azole-containing derivative and preparation method and application thereof | 沈阳药科大学 | 2023-04-04 | — | — | CN | disclosed |
| CN-112426420-B | Application of coumarin-dithiocarbamate derivative in preparation of antitumor drugs | 浙江大学 | 2021-12-28 | — | — | CN | disclosed |
| US-5922719-A | 4-AROMATIC-SUBSTITUTED-PIPERAZIN-1-YLMETHYLCHROMEN-2-ONES | WARNER-LAMBERT COMPANY (US) | 1999-07-13 | — | — | US | disclosed |
| US-5763437-A | Benzodiazepine derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0804425-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996004254-A2 | BENZODIAZEPINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-15 | — | — | WO | disclosed |
| EP-0538416-B1 | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4 ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1995-08-09 | — | — | EP | disclosed |
| EP-0538416-A4 | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY | RHONE POULENC RORER INT (US) | 1994-05-18 | — | — | EP | disclosed |
| US-5232948-A | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1993-08-03 | — | — | US | disclosed |
| EP-0538416-A1 | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B 4? ANTAGONIST ACTIVITY. | RHONE POULENC RORER INT (US) | 1993-04-28 | — | — | EP | disclosed |
| WO-1992004315-A1 | SUBSTITUTED MONOCYCLIC ARYL COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-03-19 | — | — | WO | disclosed |