Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 11/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL370424 | 1.00 | DPP7 (0.48) | DPP7DPP4DPP8SMN1; SMN2RAB9A | |
| SCHEMBL12091644 | 1.00 | DPP7 (0.48) | DPP7DPP4DPP8SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL295166 | 0.98 | DPP7 (0.47) | DPP7DPP4DPP8SMN1; SMN2RAB9A | |
| SCHEMBL10305139 | 0.86 | HIF1A (0.41) | DPP7DPP4DPP8RAB9AKMT2A | |
| SCHEMBL10030145 | 0.84 | DPP4 (0.52) | DPP7DPP4DPP8KMT2AALDH1A1 | |
| SCHEMBL2696470 | 0.84 | DPP4 (0.52) | DPP7DPP4DPP8KMT2AALDH1A1 | |
| SCHEMBL3300519 | 0.84 | HPGD (0.50) | DPP7DPP4DPP8RAB9AALDH1A1 | |
| SCHEMBL3299190 | 0.84 | HPGD (0.50) | DPP7DPP4DPP8RAB9AALDH1A1 | |
| SCHEMBL10030151 | 0.84 | DPP4 (0.52) | DPP7DPP4DPP8KMT2AALDH1A1 | |
| SCHEMBL10030138 | 0.84 | DPP4 (0.52) | DPP7DPP4DPP8KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2198864-B1 | Pharmaceutical compositions having an analgesic effect and containing 1-benzyl-1-hydroxy-2,3-diamino-propyl amines, 3-benzyl-3-hydroxy-2-amino propionic acid amides or related compounds | ALLERGAN INC (US) | 2012-03-14 | — | — | EP | disclosed |