Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.52 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.52 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10030151 | 1.00 | DPP4 (0.52) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL2696470 | 1.00 | DPP4 (0.52) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL10030138 | 1.00 | DPP4 (0.52) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL2693723 | 0.98 | DPP4 (0.51) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL10030140 | 0.98 | DPP4 (0.53) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL10030172 | 0.98 | DPP4 (0.53) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL10030169 | 0.98 | DPP4 (0.53) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL2696011 | 0.98 | DPP4 (0.51) | DPP4DPP7DPP8DPP9KCNH2 | |
| SCHEMBL15642790 | 0.98 | DPP4 (0.53) | DPP4DPP7DPP8DPP9KCNH2 | |
| Hydrochloric Acid SCHEMBL2696847 | 0.98 | DPP4 (0.51) | DPP4DPP7DPP8DPP9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168631-B2 | 3-(4-fluorophenyl)-3-hydroxy-2-amino-propionic acid amides and related compounds having analgesic activity | ALLERGAN, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-8168631-B2 | 3-(4-fluorophenyl)-3-hydroxy-2-amino-propionic acid amides and related compounds having analgesic activity | ALLERGAN, INC. (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090281085-A1 | 3-(4-FLUOROPHENYL)-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC ACTIVITY | ALLERGAN, INC. | 2009-11-12 | — | — | US | disclosed |
| US-20090281085-A1 | 3-(4-FLUOROPHENYL)-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC ACTIVITY | ALLERGAN, INC. | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281085-A1 | 3-(4-FLUOROPHENYL)-3-HYDROXY-2-AMINO-PROPIONIC ACID AMIDES AND RELATED COMPOUNDS HAVING ANALGESIC ACTIVITY | OPRL1, OPRK1, OPRM1 | DPP4 446/4885DPP7 385/4885DPP8 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.