Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968855 | 1.00 | IRAK4 (0.47) | IRAK4ALOX5PARP1BCAT2ALDH1A1 | |
| SCHEMBL6266294 | 1.00 | IRAK4 (0.47) | IRAK4ALOX5PARP1BCAT2ALDH1A1 | |
| SCHEMBL9783644 | 0.88 | IRAK4 (0.53) | IRAK4PARP1BCAT2ALDH1A1KDM4E | |
| SCHEMBL27971185 | 0.88 | ALDH1A1 (0.48) | IRAK4ALOX5PARP1ALDH1A1KDM4E | |
| SCHEMBL27971183 | 0.88 | ALDH1A1 (0.48) | IRAK4ALOX5PARP1ALDH1A1KDM4E | |
| SCHEMBL27971184 | 0.88 | ALDH1A1 (0.48) | IRAK4ALOX5PARP1ALDH1A1KDM4E | |
| SCHEMBL584940 | 0.86 | ALDH1A1 (0.55) | ALDH1A1KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL21835618 | 0.86 | IRAK4 (0.42) | IRAK4ALOX5PARP1BCAT2ALDH1A1 | |
| SCHEMBL27511285 | 0.86 | IRAK4 (0.42) | IRAK4ALOX5PARP1BCAT2ALDH1A1 | |
| SCHEMBL20425250 | 0.86 | IRAK4 (0.42) | IRAK4ALOX5PARP1BCAT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3724325-A1 | CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING | Codexis, Inc. (US) | 2020-10-21 | — | — | EP | claimed |
| WO-2019118557-A1 | CARBOXYESTERASE POLYPEPTIDES FOR AMIDE COUPLING | CODEXIS, INC. (US) | 2019-06-20 | — | — | WO | claimed |
| WO-2023018473-A1 | COMBINED DETERMINATION OF THE CONCENTRATION AND ENANTIOMERIC COMPOSITION OF CHIRAL COMPOUNDS USING SINGLE CHIROPTICAL ASSAY | GEORGETOWN UNIVERSITY (US) | 2023-02-16 | — | — | WO | disclosed |
| CN-102964195-B | Method for preparing second-level and third-level substituted amide | UNIV WENZHOU | 2015-06-24 | — | — | CN | disclosed |
| CN-102964195-A | Method for preparing second-level and third-level substituted amide | UNIV WENZHOU | 2013-03-13 | — | — | CN | disclosed |
| EP-2234995-A1 | LEUKOTRIENE B4 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009077385-A1 | LEUKOTRIENE B4 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2009-06-25 | — | — | WO | disclosed |
| EP-1960350-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2008-08-27 | — | — | EP | disclosed |
| WO-2007060162-A1 | NEW N-(1-METHYL-2PHENYLETHYL)BENZAMIDE DERIVATIVES | BAYER CROPSCIENCE SA (FR) | 2007-05-31 | — | — | WO | disclosed |
| EP-1509499-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101959-A1 | PYRROLE COMPOUNDS FOR THE TREATMENT OF PROSTAGLANDIN MEDIATED DISEASES | GLAXO GROUP LIMITED (GB) | 2003-12-11 | — | — | WO | disclosed |
| EP-0078845-A4 | ANTI-CONVULSANT. | CLARK CHARLES RANDALL | 1983-09-02 | — | — | EP | disclosed |
| EP-0078845-A1 | ANTI-CONVULSANT. | CLARK CHARLES RANDALL | 1983-05-18 | — | — | EP | disclosed |
| WO-1982004046-A1 | ANTI-CONVULSANT | CLARK CHARLES RANDALL | 1982-11-25 | — | — | WO | disclosed |