Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663814 | 0.92 | NAMPT (0.41) | NAMPTCA2TMEM97SIGMAR1 | |
| SCHEMBL30512887 | 0.86 | NAMPT (0.44) | NAMPTCA2TMEM97SIGMAR1 | |
| SCHEMBL9979410 | 0.85 | NAMPT (0.37) | NAMPTCA2 | |
| SCHEMBL8743166 | 0.84 | NAMPT (0.42) | NAMPTCA2TMEM97SIGMAR1 | |
| SCHEMBL12507078 | 0.84 | NAMPT (0.42) | NAMPTCA2TMEM97SIGMAR1 | |
| SCHEMBL3018161 | 0.81 | NAMPT (0.35) | NAMPTCA2 | |
| SCHEMBL18850244 | 0.81 | CA2 (0.41) | NAMPTCA2 | |
| SCHEMBL12507456 | 0.79 | CA2 (0.48) | NAMPTCA2TMEM97SIGMAR1 | |
| SCHEMBL11713000 | 0.78 | NAMPT (0.39) | NAMPTCA2 | |
| SCHEMBL9232549 | 0.76 | NAMPT (0.38) | NAMPTCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231200-A1 | CONTRAST AGENTS | GE Healthcare AS (NO) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009071605-A1 | CONTRAST AGENTS | GE HEALTHCARE AS (NO) | 2009-06-11 | — | — | WO | disclosed |