Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.33 |
| ▸ | RHOC | P08134 | 2/20 | 0.33 |
| ▸ | RHOA | P61586 | 2/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | ITK | Q08881 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.32 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3658255 | 0.89 | F2 (0.36) | F2EPHX2ALOX5DRD2DRD3 | |
| SCHEMBL3660860 | 0.88 | F2 (0.37) | F2DRD2DRD3KMT2ARHOC | |
| SCHEMBL977990 | 0.88 | F2 (0.37) | F2DRD2DRD3KMT2ARHOC | |
| SCHEMBL976394 | 0.85 | CA1 (0.35) | F2CYP2C9CNR1 | |
| SCHEMBL977232 | 0.85 | CNR1 (0.34) | F2EPHX2ALOX5CNR1 | |
| SCHEMBL3656172 | 0.85 | F2 (0.46) | F2EPHX2ALOX5DRD2DRD3 | |
| SCHEMBL976411 | 0.85 | IDO1 (0.34) | F2CYP2C9CNR1 | |
| SCHEMBL3655265 | 0.84 | MEN1 (0.38) | F2DRD2DRD3KMT2ACACNA1G | |
| SCHEMBL3659731 | 0.84 | F2 (0.38) | F2DRD2DRD3KMT2A | |
| SCHEMBL3655106 | 0.84 | F2 (0.38) | F2EPHX2DRD2DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234966-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Sanofi-Aventis (FR) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009106708-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | disclosed |