Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | DRD4 | P21917 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3656172 | 0.90 | F2 (0.46) | KMT2AF2LMNADRD2DRD3 | |
| SCHEMBL3659731 | 0.89 | F2 (0.38) | KMT2AF2DDR1DRD2DRD3 | |
| SCHEMBL3655106 | 0.89 | F2 (0.38) | KMT2AF2DDR1DRD2DRD3 | |
| SCHEMBL977615 | 0.87 | ALOX5 (0.39) | MEN1KMT2AF2LMNAL3MBTL1 | |
| SCHEMBL976313 | 0.85 | HPGDS (0.37) | MEN1KMT2AF2DDR1LMNA | |
| SCHEMBL977990 | 0.85 | F2 (0.37) | MEN1KMT2AF2DDR1DRD2 | |
| SCHEMBL3660860 | 0.85 | F2 (0.37) | KMT2AF2DDR1DRD2MAPT | |
| SCHEMBL977235 | 0.85 | SLC6A9 (0.36) | KMT2AF2LMNACACNA1G | |
| SCHEMBL3664045 | 0.84 | F2 (0.36) | KMT2AF2DRD2DRD3CACNA1G | |
| SCHEMBL3404166 | 0.84 | MEN1 (0.38) | MEN1KMT2AF2DDR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234966-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Sanofi-Aventis (FR) | 2010-10-06 | — | — | EP | claimed |
| WO-2009106708-A2 | AZETIDINE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | SANOFI-AVENTIS (FR) | 2009-09-03 | — | — | WO | claimed |