Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.40 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3662157 | 0.99 | KCNH2 (0.39) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3015231 | 0.81 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL3025331 | 0.81 | KCNH2 (0.54) | KCNH2KCNQ1CACNA1C | |
| Hydrochloric Acid SCHEMBL3015819 | 0.81 | KCNH2 (0.60) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3024093 | 0.81 | KCNH2 (0.53) | KCNH2KCNQ1CACNA1C | |
| SCHEMBL3026946 | 0.77 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL3666168 | 0.74 | CYP1A2 (0.37) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3023561 | 0.73 | CYP1A2 (0.37) | KCNH2 | |
| SCHEMBL3666949 | 0.72 | KCNH2 (0.33) | KCNH2 | |
| SCHEMBL3026396 | 0.69 | KCNH2 (0.45) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | claimed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | claimed |