Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3719019 | 0.83 | KCNH2 (0.37) | KCNH2 | |
| SCHEMBL3016541 | 0.83 | KCNH2 (0.50) | KCNH2 | |
| SCHEMBL3020131 | 0.83 | KCNH2 (0.46) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3027130 | 0.82 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL3026655 | 0.79 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL3022542 | 0.79 | CYP1A2 (0.36) | KCNH2 | |
| SCHEMBL3027712 | 0.79 | CRBN (0.34) | KCNH2 | |
| SCHEMBL3670290 | 0.78 | KCNH2 (0.31) | KCNH2 | |
| Hydrochloric Acid SCHEMBL3027143 | 0.78 | CRBN (0.33) | KCNH2 | |
| SCHEMBL3664047 | 0.72 | KCNH2 (0.40) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139898-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008128961-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2008-10-30 | — | — | WO | disclosed |