Benzene

Benzene

SCHEMBL3664089

C=CCOO.c1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.38
TSHR P16473 3/20 0.32
HSD17B10 Q99714 2/20 0.32
ALDH1A1 P00352 2/20 0.32
PKM P14618 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HPGD P15428 1/20 0.32
MAPK1 P28482 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
LIG1 P18858 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28529519 1.00 CYP3A4 (0.38) CYP3A4TSHRHSD17B10ALDH1A1PKM
Hydrogen Peroxide SCHEMBL28510856 0.94
SCHEMBL16402639 0.90 TSHR (0.38) CYP3A4TSHRALDH1A1CA1CA2
SCHEMBL30799 0.90
Ammonia Solution, Strong SCHEMBL2843472 0.87
Water SCHEMBL9234425 0.87
SCHEMBL1576598 0.87
Bicarbonate SCHEMBL8021109 0.85
Bicarbonate SCHEMBL1678579 0.85 CYP3A4 (0.37) CYP3A4TSHRHSD17B10ALDH1A1PKM
Bicarbonate SCHEMBL3629261 0.85 CYP3A4 (0.37) CYP3A4TSHRHSD17B10ALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986206-A Epoxidation reaction method and system 中国石油化工股份有限公司 2024-05-07 CN claimed
CN-1678548-A Process for preparing styrene or substituted styrene SHELL INT RESEARCH (NL) 2005-10-05 CN claimed
CN-219291358-U Device for coproducing epoxypropane and epoxybutane 中国石油化工股份有限公司 2023-07-04 CN disclosed
US-7692046-B2 Heterogeneous arylalkyl oxidation promoter EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-04-06 US disclosed
US-20080319234-A1 Heterogeneous arylalkyl oxidation promoter EXXONMOBIL CHEMICAL PATENTS INC. 2008-12-25 US disclosed
CN-1291953-C Process for the preparation of styrene or substituted styrene SHELL INT RESEARCH (NL) 2006-12-27 CN disclosed
EP-1654242-A2 PROCESS FOR PRODUCING ALKYLENE OXIDE Shell Internationale Research Maatschappij B.V. (NL) 2006-05-10 EP disclosed
CN-1678548-A Process for preparing styrene or substituted styrene SHELL INT RESEARCH (NL) 2005-10-05 CN disclosed
WO-2005005402-A2 PROCESS FOR PRODUCING ALKYLENE OXIDE SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) 2005-01-20 WO disclosed