⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL366025 | 0.77 | — | — | |
| SCHEMBL5178972 | 0.76 | — | — | |
| SCHEMBL269676 | 0.76 | — | — | |
| SCHEMBL18465989 | 0.72 | ALDH1A1 (0.33) | — | |
| SCHEMBL276851 | 0.69 | ALDH1A1 (0.42) | — | |
| SCHEMBL9036102 | 0.69 | — | — | |
| SCHEMBL6722126 | 0.67 | — | — | |
| SCHEMBL24790920 | 0.66 | ALDH1A1 (0.50) | — | |
| SCHEMBL12852586 | 0.65 | — | — | |
| SCHEMBL22007399 | 0.65 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646043-B1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL INC (US) | 2017-02-15 | — | — | EP | claimed |
| US-20150111815-A1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | S & T GLOBAL INC (US) | 2015-04-23 | — | — | US | claimed |
| US-20140005100-A1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL, INC. | 2014-01-02 | — | — | US | claimed |
| EP-2646043-A1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T Global Inc. (US) | 2013-10-09 | — | — | EP | claimed |
| US-20130210704-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2013-08-15 | — | — | US | claimed |
| WO-2013028615-A2 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF VIRAL INFECTIONS | S&T GOLBAL INC. (US) | 2013-02-28 | — | — | WO | claimed |
| WO-2012075494-A1 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL INC. (US) | 2012-06-07 | — | — | WO | claimed |
| WO-2012021796-A2 | NOVEL CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF A VIRAL INFECTION | S&T GLOBAL, INC. (US) | 2012-02-16 | — | — | WO | claimed |
| EP-1802650-B1 | 3-ETHER AND 3-THIOETHER SUBSTITUTED CYCLOSPORIN DERIVATIVES FOR THE TREATMENT AND PREVENTION OF HEPATITIS C INFECTION | SCYNEXIS INC (US) | 2011-10-26 | — | — | EP | claimed |
| US-7718767-B2 | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection | SCYNEXIS, INC. (US) | 2010-05-18 | — | — | US | claimed |
| US-20060160727-A1 | 3-Ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection | FLIRI HANS G | 2006-07-20 | — | — | US | claimed |
| US-20060089301-A1 | 3-ether and 3-thioether substituted cyclosporin derivatives for the treatment and prevention of hepatitis C infection | SCYNEXIS, INC. | 2006-04-27 | — | — | US | claimed |
| CN-118324867-A | Novel cyclosporin derivatives and uses thereof | 美国科技环球有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-109476705-B | Novel cyclosporin derivatives and uses thereof | 美国科技环球有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-3831841-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T Global Inc. (US) | 2021-06-09 | — | — | EP | disclosed |
| US-10647747-B2 | Cyclosporin derivatives and uses thereof | S&T GLOBAL INC. (US) | 2020-05-12 | — | — | US | disclosed |
| EP-1187819-B1 | N-SUBSTITUTED PERHYDRO DIAZINE | BASF AG (DE) | 2003-07-23 | — | — | EP | disclosed |
| US-6528455-B1 | Post or preemergence herbicides such as 3-(4-chloro-2-fluoro -5-(1-methoxycarbonyl-1-vinyloxy)phenyl)-1-methyl-6-trifluoro methyl-2,4-pyrimidinedione | BASF AKTIENGESELLSCHAFT (DE) | 2003-03-04 | — | — | US | disclosed |
| EP-1237879-A1 | PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001044204-A1 | PHENOXY AND THIOPHENOXY ACRYLIC ACID COMPOUNDS AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2001-06-21 | — | — | WO | disclosed |