Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 19/20 | 0.65 |
| ▸ | BCL2L1 | Q07817 | 15/20 | 0.65 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.54 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | ASPH | Q12797 | 1/20 | 0.54 |
| ▸ | BAD | Q92934 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5307598 | 0.90 | BCL2L1 (0.62) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425151 | 0.89 | BCL2 (0.65) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL30286306 | 0.86 | BCL2 (0.67) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425230 | 0.84 | BCL2 (0.68) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425293 | 0.82 | BCL2 (0.64) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425235 | 0.82 | BCL2 (0.57) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL1627395 | 0.80 | BCL2L1 (0.83) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL2022459 | 0.80 | BCL2 (0.79) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL2024130 | 0.80 | BCL2 (0.82) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL2025716 | 0.79 | BCL2 (0.76) | BCL2BCL2L1BCL2L2BCL2L11CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231159-A1 | METHOD OF TREATING ARTHRITIS | Abbott Laboratories (US) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009064938-A1 | METHOD OF TREATING ARTHRITIS | ABBOTT LABORATORIES (US) | 2009-05-22 | — | — | WO | disclosed |