Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 14/20 | 0.62 |
| ▸ | BCL2 | P10415 | 19/20 | 0.61 |
| ▸ | BCL2L2 | Q92843 | 2/20 | 0.51 |
| ▸ | BCL2L11 | O43521 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | ASPH | Q12797 | 1/20 | 0.51 |
| ▸ | BAD | Q92934 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664399 | 0.90 | BCL2 (0.65) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL30286306 | 0.89 | BCL2 (0.67) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL1741522 | 0.88 | BCL2 (0.55) | BCL2L1BCL2 | |
| SCHEMBL19424217 | 0.88 | BCL2L1 (0.69) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425252 | 0.88 | BCL2L1 (0.68) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425389 | 0.84 | BCL2L1 (0.63) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425149 | 0.84 | BCL2L1 (0.59) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL19425226 | 0.84 | BCL2L1 (0.62) | BCL2L1BCL2BCL2L2BCL2L11CYP2C9 | |
| SCHEMBL1741524 | 0.83 | BCL2 (0.57) | BCL2L1BCL2 | |
| SCHEMBL19425246 | 0.82 | BCL2L1 (0.58) | BCL2L1BCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007040650-A9 | APOPTOSIS PROMOTERS | ABBOTT LAB (US) | 2007-07-26 | — | — | WO | disclosed |