Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | BAZ2B | Q9UIF8 | 7/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 7/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL364388 | 0.88 | ALDH1A1 (0.43) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL367568 | 0.88 | ALDH1A1 (0.44) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL366837 | 0.86 | ALDH1A1 (0.40) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL367618 | 0.85 | BAZ2B (0.38) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL366875 | 0.85 | EGFR (0.42) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL366185 | 0.84 | CYP1A2 (0.42) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL367329 | 0.84 | BAZ2B (0.47) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL364769 | 0.84 | ALDH1A1 (0.61) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL365468 | 0.83 | ALDH1A1 (0.39) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| Potassium Ion SCHEMBL364866 | 0.83 | MAPT (0.40) | ALDH1A1MAPTKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |