Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5667980 | 0.98 | SLC6A4 (0.39) | SLC6A4SLC6A3FFAR3CYP2C19SLC6A2 | |
| Hydrochloric Acid SCHEMBL5665595 | 0.96 | SLC6A4 (0.38) | SLC6A4SLC6A3FFAR3CYP2C19SLC6A2 | |
| SCHEMBL3989202 | 0.96 | FFAR3 (0.36) | SLC6A4SLC6A3FFAR3CYP2C19SLC1A3 | |
| SCHEMBL1161505 | 0.91 | FFAR3 (0.39) | SLC6A4SLC6A3FFAR3SLC1A3SLC1A2 | |
| SCHEMBL14037320 | 0.77 | CYP2C19 (0.34) | FFAR3CYP2C19TSHR | |
| SCHEMBL9972636 | 0.77 | CYP2C19 (0.39) | FFAR3CYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL17507162 | 0.75 | CYP2C19 (0.38) | FFAR3CYP2C19USP2ALDH1A1LMNA | |
| SCHEMBL10532998 | 0.74 | CYP2C19 (0.35) | SLC6A4SLC6A3FFAR3CYP2C19SLC6A2 | |
| Hydrochloric Acid SCHEMBL1285236 | 0.73 | — | — | |
| SCHEMBL9935954 | 0.72 | CYP2C19 (0.34) | FFAR3CYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2234961-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009065406-A2 | NOVEL CYCLIC HYDROCARBON COMPOUNDS FOR THE TREATMENT OF DISEASES | LEO PHARMA A/S (DK) | 2009-05-28 | — | — | WO | disclosed |