Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3664521 | 0.96 | SLC6A4 (0.36) | FFAR3TSHRCYP2C19SLC6A4SLC6A3 | |
| SCHEMBL5667980 | 0.94 | SLC6A4 (0.39) | FFAR3TSHRCYP2C19SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL5665595 | 0.92 | SLC6A4 (0.38) | FFAR3TSHRCYP2C19SLC6A4SLC6A3 | |
| SCHEMBL1161505 | 0.91 | FFAR3 (0.39) | FFAR3SLC6A4SLC6A3SLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL1285236 | 0.78 | — | — | |
| SCHEMBL9935954 | 0.77 | CYP2C19 (0.34) | FFAR3TSHRNFKB1CYP2C19 | |
| SCHEMBL16730624 | 0.75 | FFAR3 (0.31) | FFAR3 | |
| SCHEMBL14037320 | 0.72 | CYP2C19 (0.34) | FFAR3TSHRNFKB1CYP2C19 | |
| SCHEMBL9972636 | 0.72 | CYP2C19 (0.39) | FFAR3TSHRCYP2C19 | |
| SCHEMBL9510216 | 0.71 | SLC1A1 (0.32) | SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278759-A1 | MK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| WO-2009067547-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-05-28 | — | — | WO | disclosed |