Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | SAE1 | Q9UBE0 | 2/20 | 0.65 |
| ▸ | UBA2 | Q9UBT2 | 2/20 | 0.65 |
| ▸ | APAF1 | O14727 | 1/20 | 0.65 |
| ▸ | G6PD | P11413 | 1/20 | 0.65 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.65 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.65 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | XBP1 | P17861 | 1/20 | 0.56 |
| ▸ | MPI | P34949 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL365009 | 0.88 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL364208 | 0.86 | ALDH1A1 (0.60) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL364968 | 0.86 | KDM4E (0.70) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL366637 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL367141 | 0.84 | ALDH1A1 (0.67) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL365447 | 0.83 | KDM4E (0.51) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL367088 | 0.83 | ALDH1A1 (0.74) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL364877 | 0.82 | KDM4E (0.77) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL365759 | 0.82 | ALDH1A1 (0.77) | ALDH1A1KDM4EKMT2AMAPTMEN1 | |
| SCHEMBL366986 | 0.82 | ALDH1A1 (0.77) | ALDH1A1KDM4EKMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | claimed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |
| WO-2012007007-A1 | INHIBITORS OF HDME | EPITHERAPEUTICS APS (DK) | 2012-01-19 | — | — | WO | disclosed |