Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13802842 | 0.84 | TSHR (0.45) | TSHRSMN1; SMN2MAPK1L3MBTL1GPBAR1 | |
| Benzyl Alcohol SCHEMBL9615024 | 0.84 | TSHR (0.50) | TSHRL3MBTL1TTRMTNR1B | |
| SCHEMBL758042 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2GPBAR1CYSLTR1TAAR1 | |
| SCHEMBL13803187 | 0.83 | TSHR (0.44) | TSHRSMN1; SMN2GPBAR1CYSLTR1TAAR1 | |
| SCHEMBL10584916 | 0.81 | SMN1; SMN2 (0.43) | TSHRSMN1; SMN2MAPK1L3MBTL1GPBAR1 | |
| SCHEMBL30484265 | 0.80 | DHFR (0.48) | TSHRSMN1; SMN2TAAR1 | |
| SCHEMBL16902897 | 0.80 | TSHR (0.47) | TSHRSMN1; SMN2GPBAR1CYSLTR1ENPP2 | |
| SCHEMBL112105 | 0.80 | DHFR (0.48) | TSHRSMN1; SMN2TAAR1 | |
| SCHEMBL3667661 | 0.79 | TSHR (0.41) | TSHRSMN1; SMN2MAPK1L3MBTL1GPBAR1 | |
| SCHEMBL13433919 | 0.79 | SMN1; SMN2 (0.56) | TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2240500-A1 | METHOD FOR SYNTHESIZING HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | Université de Nantes (FR) | 2010-10-20 | — | — | EP | disclosed |
| WO-2009083613-A1 | METHOD FOR SYNTHESIZING HYDROXY-BISPHOSPHONIC ACID DERIVATIVES | UNIVERSITE DE NANTES (FR) | 2009-07-09 | — | — | WO | disclosed |