Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD1 | P21728 | 12/20 | 0.71 |
| ▸ | DRD2 | P14416 | 3/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | DRD5 | P21918 | 4/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | HTR1B | P28222 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345387 | 0.88 | CYP2D6 (0.81) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| Hydrochloric Acid SCHEMBL11406845 | 0.87 | CYP2D6 (0.80) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| SCHEMBL16501317 | 0.84 | DRD1 (0.76) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| SCHEMBL3666853 | 0.84 | CYP2D6 (0.57) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| SCHEMBL3663433 | 0.80 | DRD1 (0.65) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| SCHEMBL8769108 | 0.79 | CYP2D6 (0.63) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| Trepipam SCHEMBL11704977 | 0.78 | CYP2D6 (1.00) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| Trepipam SCHEMBL29374758 | 0.78 | CYP2D6 (1.00) | DRD1DRD2CYP2D6CYP3A4DRD5 | |
| SCHEMBL16501318 | 0.75 | DRD1 (0.70) | DRD1DRD2CYP2D6CYP3A4HSD17B10 | |
| SCHEMBL8768836 | 0.74 | CYP2D6 (0.63) | DRD1DRD2CYP2D6CYP3A4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300116-A1 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method | CELLAURA TECHNOLOGIES LTD (GB) | 2011-12-08 | — | — | US | disclosed |
| US-20110300116-A1 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method | CELLAURA TECHNOLOGIES LTD (GB) | 2011-12-08 | — | — | US | disclosed |
| EP-2238248-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | Cellaura Technologies LTD (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009040555-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | CELLAURA TECHNOLOGIES LTD (GB) | 2009-04-02 | — | — | WO | disclosed |
| WO-2009040555-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | CELLAURA TECHNOLOGIES LTD (GB) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110300116-A1 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method | HAVCR2, LDLR, ADGRF1 | DRD1 3062/4885DRD2 2472/4885CYP2D6 4244/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.