Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 5/20 | 0.53 |
| ▸ | ESR1 | P03372 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B14 | Q9BPX1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3316262 | 0.86 | ALDH1A1 (0.61) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL2093017 | 0.84 | ESR2 (0.44) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL1238150 | 0.84 | ESR1 (0.50) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL29768705 | 0.84 | ESR1 (0.50) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL3317035 | 0.83 | HTT (0.45) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL2097582 | 0.82 | ESR1 (0.41) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL2092811 | 0.82 | KDM4E (0.50) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL3318792 | 0.82 | CAMK2A (0.42) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL3314874 | 0.81 | KMT2A (0.44) | ESR2ESR1ALDH1A1HSD17B10KDM4E | |
| SCHEMBL21865479 | 0.80 | ESR2 (0.46) | ESR2ESR1ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144880-B1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO KGAA (DE) | 2012-05-30 | — | — | EP | disclosed |
| EP-2144880-A1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | Henkel AG & Co. KGaA (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008135337-A1 | BIS(HYDROXYQUINOLINE) METAL COMPLEXES AS BLEACH CATALYSTS | HENKEL AG & CO. KGAA (DE) | 2008-11-13 | — | — | WO | disclosed |