SCHEMBL3665233

SCHEMBL3665233

CCS(=O)(=O)C1(C(=O)O)CC1

nearest known ligand 0.52

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
FFAR3 O14843 2/20 0.36
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17189653 0.80 LMNA (0.34) LMNASMN1; SMN2NPSR1
SCHEMBL3714980 0.74 LMNA (0.41) LMNASMN1; SMN2FFAR3NPSR1
SCHEMBL21798037 0.73 CYP3A4 (0.40) LMNASMN1; SMN2NPSR1
SCHEMBL25349015 0.73 LMNA (0.43) LMNASMN1; SMN2FFAR3NPSR1
SCHEMBL19537486 0.70 NPSR1 (0.36) LMNASMN1; SMN2FFAR3NPSR1
SCHEMBL23675613 0.69 LMNA (0.46) LMNASMN1; SMN2
SCHEMBL25048934 0.65 LMNA (0.42) LMNASMN1; SMN2FFAR3NPSR1
SCHEMBL16369615 0.64 LMNA (0.34) LMNASMN1; SMN2FFAR3NPSR1
SCHEMBL21598377 0.63 NPSR1 (0.43) LMNASMN1; SMN2FFAR3NPSR1
SCHEMBL4822241 0.63 NPSR1 (0.39) LMNASMN1; SMN2FFAR3NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667613-B2 Antiviral pyrazolopyridinone compounds NOVARTIS AG (CH) 2023-06-06 US disclosed
EP-2729447-A1 POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR H. Lundbeck A/S (DK) 2014-05-14 EP disclosed
WO-2013007621-A1 POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR H. LUNDBECK A/S (DK) 2013-01-17 WO disclosed
EP-2222655-A1 N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL Sumitomo Chemical Company, Limited (JP) 2010-09-01 EP disclosed
EP-2144898-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME Sumitomo Chemical Company, Limited (JP) 2010-01-20 EP disclosed
WO-2009066790-A1 N-CYCL0ALKYLMETHYL-2-AMIN0THIAZ0LE-5-CARB0XAMIDES FOR USE IN PLANT DISEASE CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-05-28 WO disclosed
EP-2048953-A2 INSECTICIDAL COMPOSITION Livie Biopesticides Limited (GB) 2009-04-22 EP disclosed
WO-2008130021-A2 HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-10-30 WO disclosed
WO-2008035029-A2 INSECTICIDAL COMPOSITION LIVIE BIOPESTICIDES LIMITED (GB) 2008-03-27 WO disclosed
WO-2001000581-A1 LIGANDS BASED ON CHIRAL 2-AMINO-2'-HYDROXY-1,1'-BINAPHTHYL AND RELATED FRAMEWORKS FOR ASYMMETRIC CATALYSIS THE PENN STATE RESEARCH FOUNDATION (US) 2001-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667613-B2 Antiviral pyrazolopyridinone compounds ZC3HAV1, TYMP, ZC3HAV1L LMNA 3435/4885SMN1; SMN2 1995/4885FFAR3 3997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.