Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 5/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2569632 | 0.88 | DRD1 (0.53) | CYP3A4CYP2D6DRD1HTR2ADRD2 | |
| SCHEMBL3663433 | 0.82 | DRD1 (0.65) | CA1CA2CA9CA14SLC6A2 | |
| SCHEMBL11393016 | 0.82 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL18085059 | 0.82 | SLC6A2 (0.76) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL3666853 | 0.82 | CYP2D6 (0.57) | CA1CA2CA9CA14SLC6A2 | |
| SCHEMBL2566550 | 0.81 | DRD1 (0.58) | CYP3A4CYP2D6DRD1HTR2AMEN1 | |
| Hydrochloric Acid SCHEMBL11797561 | 0.81 | SLC6A4 (0.67) | CA1CA2CA9CA14SLC6A2 | |
| SCHEMBL16501316 | 0.78 | DRD1 (0.54) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 | |
| SCHEMBL10414724 | 0.73 | CA1 (0.53) | CA1CA2CA9CA14CYP3A4 | |
| SCHEMBL9405364 | 0.73 | DRD1 (0.59) | SLC6A2SLC6A4SLC6A3CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110300116-A1 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method | CELLAURA TECHNOLOGIES LTD (GB) | 2011-12-08 | — | — | US | disclosed |
| US-20110300116-A1 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method | CELLAURA TECHNOLOGIES LTD (GB) | 2011-12-08 | — | — | US | disclosed |
| EP-2238248-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | Cellaura Technologies LTD (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009040555-A2 | A METHOD FOR GENERATING A RECOMBINANT CLONAL CELL LINE AND NOVEL REAGENTS FOR USE IN THE METHOD | CELLAURA TECHNOLOGIES LTD (GB) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110300116-A1 | Method for Generating a Recombinant Clonal Cell Line and Novel Reagents for Use in the Method | HAVCR2, LDLR, ADGRF1 | CA1 3212/4885CA2 4023/4885CA9 4342/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.