Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 5/20 | 0.43 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2059299 | 0.89 | ALOX15 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL1187895 | 0.89 | ALOX15 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL2059424 | 0.89 | ALOX15 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL1187666 | 0.89 | ALOX15 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL1188341 | 0.88 | ALOX15 (0.44) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL1188579 | 0.88 | ALOX15 (0.44) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL1187917 | 0.86 | ALOX15 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL22630563 | 0.86 | ALOX15 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL2059265 | 0.86 | PTPN2 (0.43) | ALOX15PTPN2PTPN1CDC25B | |
| SCHEMBL17416757 | 0.85 | PTPN2 (0.37) | ALOX15PTPN2PTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220030-B1 | 4- (P-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES | EDISON PHARMACEUTICALS INC (US) | 2016-01-13 | — | — | EP | claimed |
| EP-2220030-A2 | 4- (P-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES | Edison Pharmaceuticals, Inc. (US) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009061744-A2 | 4- (P-QUINONYL)-2-HYDROXYBUTANAMIDE DERIVATIVES FOR TREATMENT OF MITOCHONDRIAL DISEASES | EDISON PHARMACEUTICALS, INC. (US) | 2009-05-14 | — | — | WO | disclosed |