Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.50 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.50 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16390835 | 1.00 | MAOA (0.52) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17527067 | 1.00 | MAOA (0.52) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17508108 | 0.98 | MAOA (0.54) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL17527074 | 0.96 | MAOA (0.52) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL1983580 | 0.96 | HDAC3 (0.54) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8708196 | 0.96 | HDAC3 (0.54) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8993155 | 0.96 | HDAC3 (0.54) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8027241 | 0.96 | HDAC3 (0.50) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5741392 | 0.94 | MAOA (0.54) | MAOAHDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL713789 | 0.92 | CARM1 (0.53) | MAOAHDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139461-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | Recepticon Aps (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113364-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | RECEPTICON APS (DK) | 2008-09-25 | — | — | WO | disclosed |