Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP8B1 | Q9UNU6 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 9/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666283 | 1.00 | CYP8B1 (0.41) | CYP8B1KCNH2KDM4EMEN1KMT2A | |
| SCHEMBL10078697 | 0.81 | CYP8B1 (0.42) | CYP8B1KCNH2KDM4EMEN1KMT2A | |
| SCHEMBL10078699 | 0.81 | CYP8B1 (0.42) | CYP8B1KCNH2KDM4EMEN1KMT2A | |
| SCHEMBL1224380 | 0.76 | ALDH1A1 (0.42) | CYP8B1KCNH2ALDH1A1 | |
| SCHEMBL1222848 | 0.73 | CYP8B1 (0.42) | CYP8B1KCNH2 | |
| SCHEMBL3630741 | 0.73 | EHMT2 (0.48) | CYP8B1KCNH2 | |
| SCHEMBL16986064 | 0.72 | CYP8B1 (0.47) | CYP8B1KCNH2 | |
| SCHEMBL1223764 | 0.71 | KCNH2 (0.42) | KCNH2 | |
| SCHEMBL9516978 | 0.71 | PDE4A (0.44) | MEN1KMT2AUSP30ALDH1A1SMN1; SMN2 | |
| SCHEMBL1223261 | 0.71 | ALDH1A1 (0.45) | CYP8B1KCNH2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2915813-A1 | Oxazolidinone antibiotics | Actelion Pharmaceuticals Ltd. (CH) | 2015-09-09 | — | — | EP | disclosed |
| EP-2905283-A1 | Oxazolidinone antibiotics | Actelion Pharmaceuticals Ltd. (CH) | 2015-08-12 | — | — | EP | disclosed |
| US-8217029-B2 | Oxazolidinone antibiotics | ACTELION PHARMACEUTICALS LTD (CH) | 2012-07-10 | — | — | US | disclosed |
| EP-2144910-A2 | OXAZOLIDINONE ANTIBIOTICS | Actelion Pharmaceuticals Ltd. (CH) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008126034-A2 | OXAZOLIDINONE ANTIBIOTICS | ACTELION PHARMACEUTICALS LTD (CH) | 2008-10-23 | — | — | WO | disclosed |