Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 2/20 | 0.30 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | CCR5 | P51681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666040 | 0.87 | — | — | |
| SCHEMBL13145546 | 0.86 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL3084560 | 0.86 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL3092417 | 0.86 | MMP2 (0.39) | MMP2MMP9MMP3 | |
| SCHEMBL3082458 | 0.86 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL3072570 | 0.86 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL31003825 | 0.86 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL3088632 | 0.85 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL31003725 | 0.85 | CNR1 (0.33) | MMP2MMP9 | |
| SCHEMBL3093775 | 0.83 | MMP2 (0.43) | MMP2MMP9MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139856-A1 | SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONE-COMPOUNDS | Topotarget A/S (DK) | 2010-01-06 | — | — | EP | claimed |
| WO-2008129075-A1 | SUBSTITUTED 3-(4-HYDROXYPHENYL)-INDOLIN-2-ONE-COMPOUNDS | TOPOTARGET A/S (DK) | 2008-10-30 | — | — | WO | claimed |