Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29647544 | 1.00 | ALDH1A1 (0.48) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Water SCHEMBL7865200 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| SCHEMBL8036043 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| SCHEMBL29212557 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Biphenyl SCHEMBL9579764 | 0.97 | ALDH1A1 (0.50) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Hydrochloric Acid SCHEMBL28896072 | 0.97 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Biphenyl SCHEMBL4395361 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Biphenyl SCHEMBL7872958 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Biphenyl SCHEMBL11371012 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 | |
| Biphenyl SCHEMBL7874532 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP2A6HPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 517 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12344586-B2 | Process for the preparation of biphenylamines | ADAMA MAKHTESHIM LTD. (IL) | 2025-07-01 | — | — | US | claimed |
| CN-119978324-A | Novel naphthalimide building unit and preparation method and application of conjugated polymer thereof | 中国科学院化学研究所 | 2025-05-13 | — | — | CN | claimed |
| CN-118955537-A | Tetraazaisoindigo derivative and preparation method thereof | 江汉大学 | 2024-11-15 | — | — | CN | claimed |
| CN-118599091-A | D-A-D-C structure pyrrolopyrrole diketo terpolymer and synthetic method and application thereof | 北京印刷学院 | 2024-09-06 | — | — | CN | claimed |
| US-12024136-B2 | Ultra-fast curing scratch-resistant headlight restoration coating | ILLINOIS TOOL WORKS INC. (US) | 2024-07-02 | — | — | US | claimed |
| CN-118184967-A | Functional side chain substituted pyrrolopyrrole diketo-base terpolymer and preparation method and application thereof | 北京印刷学院 | 2024-06-14 | — | — | CN | claimed |
| CN-114349594-B | Method and reactor for preparing polyhalogenated hydrocarbon | 西安近代化学研究所 | 2024-02-20 | — | — | CN | claimed |
| CN-117069717-A | 2, 6-naphthyridine micromolecule derivative and preparation method thereof | 江汉大学 | 2023-11-17 | — | — | CN | claimed |
| CN-112543750-B | Process for producing fluorinated aromatic secondary amine compound | 日产化学株式会社 | 2023-11-03 | — | — | CN | claimed |
| CN-116120526-A | BN compound and preparation method thereof | 上海恩索伯新能源科技有限公司 | 2023-05-16 | — | — | CN | claimed |
| EP-1127886-B1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | HOFFMANN LA ROCHE (CH) | 2003-05-07 | — | — | EP | claimed |
| US-6552204-B1 | Lactonization of an acyl halide and a ketene acetal or reacting acyl halide with malonate half acid then cyclizing; high yield | ROCHE COLORADO CORPORATION | 2003-04-22 | — | — | US | claimed |
| EP-0906916-B1 | PROCESS FOR PRODUCING ORGANOPHOSPHORUS COMPOUNDS | SANKO KAIHATSU KAGAKU KENK (JP) | 2003-03-12 | — | — | EP | claimed |
| CN-1319596-A | Synthesis of 3,6-dialkyl 5,6-dihydro-4-hydroxide-2H-pyran-2-ketone | HOFFMANN LA ROCHE (CH) | 2001-10-31 | — | — | CN | claimed |
| EP-1127886-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-2H-pyran-2one | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-29 | — | — | EP | claimed |
| CN-1069899-C | Process for preparing azepines and intermediates | HOFFMANN LA ROCHE (CH) | 2001-08-22 | — | — | CN | claimed |
| WO-2000068237-A1 | PD- AND NI COMPLEXES OF BIPHENYL-2-YL-PHOSPHANES AND THEIR USE IN CATALYTIC C,C-, C,N- AND C,O-COUPLINGS | CLARIANT GMBH (DE) | 2000-11-16 | — | — | WO | claimed |
| US-6107506-A | Process for producing 2-(2-hydroxyphenyl) phenylphosphinic acid and derivatives | SANKO KAIHATSU KAGAKU KENKYUSHO (JP) | 2000-08-22 | — | — | US | claimed |
| EP-0906916-A1 | PROCESS FOR PRODUCING ORGANOPHOSPHORUS COMPOUNDS | Sanko Kaihatsu Kagaku Kenkyusho (JP) | 1999-04-07 | — | — | EP | claimed |
| CN-1168374-A | Process for preparing azepines and intermediates | HOFFMANN LA ROCHE (CH) | 1997-12-24 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12344586-B2 | Process for the preparation of biphenylamines | DDT, AGPS, PAH | ALDH1A1 974/4885HSD17B10 2093/4885CYP2A6 565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.