Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.38 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2587462 | 0.84 | SCN1A (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2473860 | 0.84 | SCN1A (0.36) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3637878 | 0.84 | CA12 (0.35) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3807346 | 0.76 | SCN1A (0.34) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3814655 | 0.72 | HSPA5 (0.48) | HSPA5THRBPRKCIAKR1B1CNR2 | |
| SCHEMBL5195832 | 0.71 | LMNA (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2471593 | 0.70 | CA12 (0.33) | CA12CA1CA2CA7CA9 | |
| Hydrochloric Acid SCHEMBL2587948 | 0.70 | CA12 (0.33) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4380290 | 0.70 | CA12 (0.43) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11790742 | 0.69 | HSPA5 (0.41) | HSPA5KMT2ATHRBEGFRNOX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170826-A1 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | Techfields Inc (US) | 2010-04-07 | — | — | EP | disclosed |
| WO-2008149181-A1 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | TECHFIELDS INC (US) | 2008-12-11 | — | — | WO | disclosed |