SCHEMBL3667632

SCHEMBL3667632

C=CC(=O)OC(C)(C)CC1CO1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
THRA P10827 1/20 0.34
THRB P10828 1/20 0.34
TSHR P16473 3/20 0.32
MAPK1 P28482 2/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7778354 0.86 ALDH1A1 (0.35) ALDH1A1TSHRMAPK1TP53CYP3A4
SCHEMBL7778355 0.80 HCAR2 (0.38) ALDH1A1TSHRMAPK1
SCHEMBL7778356 0.80 HCAR2 (0.38) ALDH1A1TSHRMAPK1
SCHEMBL13864108 0.80 TSHR (0.41) ALDH1A1TSHRMAPK1TP53CYP3A4
SCHEMBL14473469 0.78 ALDH1A1 (0.39) ALDH1A1TSHRMAPK1TP53CYP3A4
SCHEMBL14473467 0.78 ALDH1A1 (0.38) ALDH1A1TSHRMAPK1TP53CYP3A4
Glycidol SCHEMBL27496988 0.78 ALDH1A1 (0.36) ALDH1A1THRATHRBTSHRMAPK1
SCHEMBL27697907 0.77 ALDH1A1 (0.44) ALDH1A1THRBTSHRMAPK1TP53
SCHEMBL14473383 0.77 ALDH1A1 (0.36) ALDH1A1TSHRMAPK1TP53CYP3A4
SCHEMBL28109298 0.76 ALDH1A1 (0.54) ALDH1A1THRBTSHRMAPK1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8241753-B2 Composite thermoplastic elastomer structures with high adhesion performance and uses for the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-08-14 US claimed
US-20080299397-A1 Composite thermoplastic elastomer structures with high adhesion performance and uses for the same CELANESE INTERNATIONAL CORPORATION 2008-12-04 US claimed
US-20180340059-A1 Compositions and Heavy Layers Comprising the Same EXXONMOBIL CHEMICAL PATENTS INC. 2018-11-29 US disclosed
US-9714341-B2 Biodegradable polyester-based blends WASHINGTON STATE UNIVERSITY (US) 2017-07-25 US disclosed
US-20160053112-A1 BIODEGRADABLE POLYESTER-BASED BLENDS EMPIRE TECHNOLOGY DEVELOPMENT LLC 2016-02-25 US disclosed
WO-2014149024-A1 BIODEGRADABLE POLYESTER-BASED BLENDS WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2014-09-25 WO disclosed
US-8241753-B2 Composite thermoplastic elastomer structures with high adhesion performance and uses for the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-08-14 US disclosed
CN-102337140-A Liquid crystal aligning agent for retardation film, liquid crystal alignment film for retardation film, and retardation film and process for production thereof JSR CORP 2012-02-01 CN disclosed
US-7691944-B2 Primer composition and uses thereof NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2010-04-06 US disclosed
US-20100044914-A1 Primer composition and uses thereof NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2010-02-25 US disclosed
US-7579405-B2 Primer composition and uses thereof NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2009-08-25 US disclosed
US-20080299397-A1 Composite thermoplastic elastomer structures with high adhesion performance and uses for the same CELANESE INTERNATIONAL CORPORATION 2008-12-04 US disclosed
US-7220484-B2 Polymeric nanocomposites comprising epoxy-functionalized graft polymer NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2007-05-22 US disclosed
US-20050261422-A1 Primer composition and uses thereof NATIONAL RESEARCH COUNCIL OF CANADA 2005-11-24 US disclosed
US-20050191490-A1 POLYMERIC NANOCOMPOSITES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2005-09-01 US disclosed
EP-0487678-B1 THERMOPLASTIC ELASTOMERS AND METHOD FOR MAKING GEN ELECTRIC (US) 1995-11-29 EP disclosed
EP-0275141-B1 EPOXY CONTAINING IMPACT MODIFIERS FOR THERMOPLASTIC RESINS COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1993-07-28 EP disclosed
US-5008342-A Modified rubber CITIBANK, N.A., AS COLLATERAL AGENT 1991-04-16 US disclosed
EP-0275141-A2 Epoxy containing impact modifiers for thermoplastic resins COPOLYMER RUBBER & CHEMICAL CORPORATION (US) 1988-07-20 EP disclosed
EP-0274744-A2 Epoxy containing impact modifiers for thermoplastic resins GENERAL ELECTRIC COMPANY (US) 1988-07-20 EP disclosed