Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 19/20 | 0.81 |
| ▸ | FABP3 | P05413 | 1/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407796 | 0.96 | DHODH (0.74) | DHODHFABP3FABP4 | |
| SCHEMBL468472 | 0.90 | DHODH (1.00) | DHODHFABP3FABP4 | |
| SCHEMBL2404053 | 0.89 | DHODH (0.82) | DHODH | |
| SCHEMBL2404587 | 0.89 | DHODH (0.63) | DHODH | |
| SCHEMBL3670177 | 0.88 | DHODH (0.82) | DHODH | |
| SCHEMBL2403928 | 0.85 | DHODH (0.74) | DHODH | |
| SCHEMBL2404343 | 0.84 | DHODH (0.57) | DHODH | |
| SCHEMBL2405939 | 0.84 | DHODH (0.75) | DHODH | |
| SCHEMBL2404076 | 0.83 | DHODH (0.59) | DHODH | |
| SCHEMBL3665570 | 0.79 | DHODH (0.82) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2210615-A1 | Combinations comprising methotrexate and DHODH inhibitors | Almirall, S.A. (ES) | 2010-07-28 | — | — | EP | claimed |
| US-20140005178-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2014-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140005178-A1 | AZABIPHENYLAMINOBENZOIC ACID DERIVATIVES AS DHODH INHIBITORS | DHODH, DPYD, DLD | DHODH 1/4885FABP3 1260/4885FABP4 663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.