SCHEMBL3667804

SCHEMBL3667804

O=C(O)c1cc(O)cc(OC(=O)c2cc3ccccc3cc2O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.49
GPBAR1 Q8TDU6 1/20 0.48
MEN1 O00255 5/20 0.48
KMT2A Q03164 5/20 0.48
MAPT P10636 6/20 0.47
LMNA P02545 1/20 0.47
TP53 P04637 1/20 0.47
CYP3A4 P08684 1/20 0.47
ADORA3 P0DMS8 1/20 0.47
CHRM1 P11229 1/20 0.47
TBXA2R P21731 1/20 0.47
SLC6A2 P23975 1/20 0.47
PDE4A P27815 1/20 0.47
ADRA1A P35348 1/20 0.47
KDR P35968 1/20 0.47
SLC6A3 Q01959 1/20 0.47
HDAC6 Q9UBN7 1/20 0.47
HPGD P15428 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2273560 0.93 MEN1 (0.48) SMN1; SMN2GPBAR1MEN1KMT2AMAPT
SCHEMBL15611159 0.85 CA12 (0.51) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL1098951 0.82 HPGD (0.67) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL15330418 0.81 KMT2A (0.58) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL28446937 0.79 HSD17B10 (0.52) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL618766 0.79 CA12 (0.61) SMN1; SMN2GPBAR1MEN1KMT2AMAPT
SCHEMBL7121986 0.77 MAPT (0.57) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL7913602 0.77 MAPT (0.56) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL13064975 0.76 POLB (0.65) SMN1; SMN2MEN1KMT2AMAPTLMNA
SCHEMBL1220041 0.76 HPGD (0.60) SMN1; SMN2MEN1KMT2AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012536-B2 Water-borne paints based on epoxy resins ALLNEX AUSTRIA GMBH (AT) 2015-04-21 US disclosed
EP-2242810-A1 WATER-BORNE PAINTS BASED ON EPOXY RESINS Cytec Austria GmbH (AT) 2010-10-27 EP disclosed
EP-2028244-A1 Water-borne paints based on epoxy resins Cytec Surface Specialties Austria GmbH (AT) 2009-02-25 EP disclosed
WO-2009016162-A1 WATER-BORNE PAINTS BASED ON EPOXY RESINS CYTEC SURFACE SPECIALTIES AUSTRIA GMBH (AT) 2009-02-05 WO disclosed