Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 8/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8872239 | 0.83 | CYP1A2 (0.55) | MEN1KMT2A | |
| SCHEMBL12068491 | 0.83 | CYP1A2 (0.55) | MEN1KMT2A | |
| SCHEMBL3244612 | 0.83 | SLC6A2 (0.45) | MEN1KMT2ASLC6A4OPRD1SLC6A2 | |
| SCHEMBL1101369 | 0.82 | MEN1 (0.59) | MEN1KMT2ASLC6A4OPRD1SLC6A2 | |
| SCHEMBL7368104 | 0.82 | MEN1 (0.59) | MEN1KMT2ASLC6A4OPRD1SLC6A2 | |
| SCHEMBL8097811 | 0.81 | CYP1A2 (0.57) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7459908 | 0.81 | LMNA (0.49) | MEN1KMT2ASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL13293355 | 0.81 | CYP1A2 (0.57) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL3997950 | 0.81 | SLC6A2 (0.44) | MEN1KMT2ASLC6A4OPRD1SLC6A2 | |
| Hydrochloric Acid SCHEMBL3252467 | 0.81 | SLC6A2 (0.44) | MEN1KMT2ASLC6A4OPRD1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8753875-B2 | Compositions and means for diagnosing microbial infections | STATENS SERUM INSTITUT (DK) | 2014-06-17 | — | — | US | disclosed |
| EP-2150532-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | Evotec AG (DE) | 2010-02-10 | — | — | EP | disclosed |
| US-20090068696-A1 | COMPOSITIONS AND MEANS FOR DIAGNOSING MICROBIAL INFECTIONS | STATENS SERUM INSTITUT | 2009-03-12 | — | — | US | disclosed |
| WO-2008122787-A1 | PIPERAZINE COMPOUNDS FOR THE INHIBITION OF HAEMATOPOIETIC PROSTAGLANDIN D SYNTHASE | EVOTEC AG (DE) | 2008-10-16 | — | — | WO | disclosed |