Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.52 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 4/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586917 | 0.88 | PPARA (0.55) | PPARASYKATMPPARGCTSS | |
| SCHEMBL8564724 | 0.88 | PPARA (0.55) | PPARASYKATMPPARGCTSS | |
| SCHEMBL1587188 | 0.87 | PPARA (0.54) | PPARASYKATMPPARGCTSS | |
| SCHEMBL1684537 | 0.81 | PPARA (0.48) | PPARASYKATMPPARGCTSS | |
| SCHEMBL8567696 | 0.81 | PPARA (0.54) | PPARASYKATMPPARGCTSS | |
| SCHEMBL8567700 | 0.81 | PPARA (0.54) | PPARASYKATMPPARGCTSS | |
| SCHEMBL18407225 | 0.76 | PPARA (0.69) | PPARASYKATMPPARGCTSS | |
| SCHEMBL15341687 | 0.76 | SYK (0.62) | PPARASYKATMPPARGCTSS | |
| SCHEMBL1363391 | 0.76 | PPARA (0.59) | PPARASYKATMPPARGCTSS | |
| SCHEMBL1569316 | 0.76 | PPARA (0.59) | PPARASYKATMPPARGCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2231280-A2 | ORGANIC COMPOUNDS | Novartis AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009074575-A2 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2009-06-18 | — | — | WO | disclosed |