Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.55 |
| ▸ | PPARG | P37231 | 2/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.49 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP3 | P08254 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1586917 | 1.00 | PPARA (0.55) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL1587188 | 0.90 | PPARA (0.54) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL3668697 | 0.88 | PPARA (0.52) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL1569316 | 0.86 | PPARA (0.59) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL1363391 | 0.86 | PPARA (0.59) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL35211707 | 0.86 | PPARA (0.59) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL1684537 | 0.84 | PPARA (0.48) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL8567696 | 0.83 | PPARA (0.54) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL8567700 | 0.83 | PPARA (0.54) | PPARAPPARGCTSSSYKATM | |
| SCHEMBL212797 | 0.83 | PPARA (0.65) | PPARAPPARGCTSSSYKATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5719141-A | HYPOTENSIVE AGENTS | NOVARTIS CORPORATION (US) | 1998-02-17 | — | — | US | disclosed |