SCHEMBL3668820

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30706932	1.00	CYP3A4 (0.48)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL30761055	0.82	ALDH1A1 (0.52)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL19949172	0.82	ALDH1A1 (0.52)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL9566859	0.82	CYP3A4 (0.50)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL17232424	0.82	CYP3A4 (0.50)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL5160048	0.82	ALDH1A1 (0.43)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL28404592	0.80	POLB (0.38)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL11067091	0.80	MAPT (0.42)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL31159576	0.80	CYP3A4 (0.48)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2
	SCHEMBL10738156	0.77	CYP3A4 (0.50)	CYP3A4TSHRMAPK1ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.