Phenylalanine

Phenylalanine

SCHEMBL366883

NCc1ccccc1.N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 6/20 0.85
ALPI P09923 1/20 0.85
PKM P14618 1/20 0.85
PTGS1 P23219 1/20 0.85
XIAP P98170 1/20 0.85
SLC1A3 P43003 2/20 0.61
SLC1A2 P43004 2/20 0.61
SLC1A1 P43005 2/20 0.61
GRIA2 P42262 1/20 0.57
SLC15A1 P46059 1/20 0.56
NOS3 P29474 2/20 0.55
NOS1 P29475 2/20 0.55
NOS2 P35228 2/20 0.55
LOXL2 Q9Y4K0 1/20 0.54
CYP1A2 P05177 1/20 0.53
LTA4H P09960 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL15656470 0.95 SLC7A5 (0.76) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL43410 0.92 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL43411 0.92 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL662103 0.92 SLC7A5 (0.71) SLC7A5ALPIPKMPTGS1XIAP
SCHEMBL23159186 0.92 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
D-Phenylalanine SCHEMBL837632 0.92 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL43671 0.92 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL8118 0.92 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8119 0.92 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL16398196 0.92 SLC7A5 (1.00) SLC7A5ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2568994-A2 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA Polytechnic Institute of New York University (US) 2013-03-20 EP disclosed
WO-2011143383-A9 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2012-02-16 WO disclosed
WO-2011143383-A3 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2012-01-19 WO disclosed
WO-2011143383-A2 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2011-11-17 WO disclosed