SCHEMBL43411

SCHEMBL43411

NCc1ccc(C[C@H](N)C(=O)O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 3/20 0.71
PTGS1 P23219 3/20 0.70
ALPI P09923 1/20 0.70
PKM P14618 1/20 0.70
XIAP P98170 1/20 0.70
HIF1A Q16665 4/20 0.59
ALOX15 P16050 3/20 0.59
KDM4E B2RXH2 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
HSD17B10 Q99714 2/20 0.59
USP2 O75604 1/20 0.59
EGFR P00533 1/20 0.59
LCK P06239 1/20 0.59
FYN P06241 1/20 0.59
ADORA3 P0DMS8 1/20 0.59
HTR2A P28223 1/20 0.59
PTGS2 P35354 1/20 0.59
RECQL P46063 1/20 0.59
TPH1 P17752 1/20 0.59
GRB2 P62993 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL662103 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL43410 1.00 SLC7A5 (0.71) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL366883 0.92 SLC7A5 (0.85) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL2310526 0.91 SLC7A5 (0.83) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL15656470 0.87 SLC7A5 (0.76) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL14233567 0.86 SLC7A5 (0.69) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL156189 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL837014 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL16581271 0.85 SLC7A5 (0.74) SLC7A5PTGS1ALPIPKMXIAP
SCHEMBL485684 0.85 SLC7A5 (0.67) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1594 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 US claimed
US-12351573-B2 Compounds for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2025-07-08 US claimed
WO-2024030977-A2 NOVEL MELANOCORTIN ANALOGS SIGHTSTREAM BIOTHERAPEUTICS, INC. (US) 2024-02-08 WO claimed
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ZEALAND PHARMA A/S (DK) 2023-12-21 US claimed
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES PEPTIDREAM INC (JP) 2023-08-17 US claimed
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ZEALAND PHARMA A/S (DK) 2023-08-01 US claimed
WO-2023084234-A1 ANTI-INFECTIVE BICYCLIC PEPTIDE LIGANDS BICYCLETX LIMITED (GB) 2023-05-19 WO claimed
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2023-04-13 US claimed
US-11566057-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors MERCK SHARP & DOHME LLC (US) 2023-01-31 US claimed
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2022-11-24 US claimed
US-20050119190-A1 Inhibitors of the blood-clotting factor xa, production thereof and use of the same CURACYTE AG (DE) 2005-06-02 US claimed
US-6610826-B1 Useful for treatment of disorders caused by implants, defects, inflammations and of osteolytic disorders such as osteoporosis, thrombosis, cardiac infarction and arteriosclerosis MERCK PATENT DEPARTMENT (DE) 2003-08-26 US claimed
US-5721210-A OLIGOPEPTIDES AS ANTIINFLAMMATORY AGENTS OR INTEGRIN RECEPTOR ANTAGONISTS TANABE SEIYAKU CO., LTD. (JP) 1998-02-24 US claimed
EP-0627925-A4 TRYPSIN INHIBITORS. CORVAS INT INC (US) 1997-07-30 EP claimed
US-5534498-A TREATMENT OF PANCREATITIS CORVAS INTERNATIONAL, INC. (US) 1996-07-09 US claimed
EP-0627925-A1 TRYPSIN INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1994-12-14 EP claimed
EP-0538399-A4 1994-05-04 EP claimed
WO-1993014779-A1 TRYPSIN INHIBITORS CORVAS INTERNATIONAL, INC. (US) 1993-08-05 WO claimed
EP-0538399-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO., LTD. (JP) 1993-04-28 EP claimed
WO-1992000995-A1 CYCLIC CELL ADHESION MODULATION COMPOUNDS TANABE SEIYAKU CO. LTD. (JP) 1992-01-23 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12351573-B2 Compounds for use in synthesis of peptidomimetics DNPEP, NPEPPS, PAM SLC7A5 1166/4885PTGS1 2925/4885ALPI 2783/4885
US-20050119190-A1 Inhibitors of the blood-clotting factor xa, production thereof and use of the same SERPINC1, TFPI, F11 SLC7A5 4712/4885PTGS1 1407/4885ALPI 2075/4885
US-20230111252-A1 THIOSEMICARBAZATES AND USES THEREOF TST, ABAT, AADAC SLC7A5 378/4885PTGS1 4428/4885ALPI 2000/4885
US-20220372022-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS DNPEP, NPEPPS, PAM SLC7A5 1166/4885PTGS1 2925/4885ALPI 2783/4885
US-11566057-B2 Long-acting co-agonists of the glucagon and GLP-1 receptors GLP1R, GCGR, GIPR SLC7A5 3291/4885PTGS1 1221/4885ALPI 1169/4885
US-20230257343-A1 NOVEL AMINO ACID DERIVATIVES DNPEP, BCAT1, ANPEP SLC7A5 21/4885PTGS1 3737/4885ALPI 3748/4885
US-20230406884-A1 CYCLIC PEPTIDES MULTIMERS TARGETING ALPHA-4-BETA-7 INTEGRIN ITGB7, ITGB4, ITGA4 SLC7A5 2407/4885PTGS1 4496/4885ALPI 3773/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT SLC7A5 64/4885PTGS1 3489/4885ALPI 2887/4885
US-11713338-B2 Cyclic peptides multimers targeting α-4-β-7 integrin ITGB7, ITGB4, ITGA4 SLC7A5 2493/4885PTGS1 4530/4885ALPI 3753/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.