SCHEMBL3668951

SCHEMBL3668951

CCCc1c(Cc2ccc(N)c(CCl)c2CCC)ccc(N)c1CCl

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 1/20 0.33
SKP2 Q13309 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3671803 0.89 SKP2 (0.42) NOS2SKP2
SCHEMBL3674257 0.89 NOS2 (0.33) NOS2SKP2
SCHEMBL814318 0.88 NOS2 (0.37) NOS2SKP2
SCHEMBL3675878 0.85
SCHEMBL3673502 0.81 NOS2 (0.33) NOS2SKP2
SCHEMBL3678219 0.81 NOS2 (0.33) NOS2SKP2
SCHEMBL3674203 0.80 NOS2 (0.33) NOS2
SCHEMBL3676818 0.80 NOS2 (0.33) NOS2SKP2
SCHEMBL1534142 0.78 NOS2 (0.38) NOS2SKP2
SCHEMBL3674983 0.77 SKP2 (0.41) NOS2SKP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1426392-B1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL CO (JP) 2010-02-24 EP disclosed
US-6960640-B2 Composition for optical material MITSUBISHI GAS CHEMICAL CO., LTD. (JP) 2005-11-01 US disclosed
US-20040147708-A1 Composition for optical material MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-07-29 US disclosed
EP-1426392-A1 COMPOSITION FOR OPTICAL MATERIAL MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2004-06-09 EP disclosed