Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.51 |
| ▸ | HRH2 | P25021 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2323553 | 1.00 | SIGMAR1 (0.51) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL30066251 | 0.98 | SIGMAR1 (0.50) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL5724530 | 0.98 | SIGMAR1 (0.50) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL19489977 | 0.97 | SIGMAR1 (0.49) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL25260908 | 0.93 | SIGMAR1 (0.46) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL15775872 | 0.93 | SIGMAR1 (0.46) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL16317494 | 0.90 | SIGMAR1 (0.44) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL6424590 | 0.90 | SIGMAR1 (0.46) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL19489860 | 0.89 | SIGMAR1 (0.45) | SIGMAR1HRH2HRH1MEN1KMT2A | |
| SCHEMBL19489937 | 0.89 | SIGMAR1 (0.45) | SIGMAR1HRH2HRH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155262-A2 | COMPOSITIONS FOR TARGETED IMAGING AND THERAPY | Radiomedix Inc. (US) | 2010-02-24 | — | — | EP | disclosed |
| WO-2008119036-A2 | COMPOSITIONS FOR TARGETED IMAGING AND THERAPY | RADIOMEDIX INC. (US) | 2008-10-02 | — | — | WO | disclosed |