SCHEMBL3669145

SCHEMBL3669145

Cl[Zr](Cl)(C1C(c2ccco2)=Cc2c(-c3ccccc3)cccc21)C1C(c2ccco2)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMARCA2 P51531 1/20 0.35
PBRM1 Q86U86 1/20 0.35
ALDH1A1 P00352 4/20 0.33
HSD17B10 Q99714 4/20 0.33
KDM4E B2RXH2 3/20 0.33
HPGD P15428 2/20 0.33
PIK3R1 P27986 1/20 0.33
PIK3CA P42336 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
ESR1 P03372 1/20 0.33
POLB P06746 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
BLM P54132 1/20 0.33
CASP7 P55210 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7732779 0.90 KDM4E (0.33) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
SCHEMBL7061941 0.84 KDM4E (0.32) ALDH1A1HSD17B10KDM4EHPGDMEN1
SCHEMBL7730639 0.81 SMARCA2 (0.35) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
SCHEMBL28036479 0.80 SMARCA2 (0.37) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
SCHEMBL7065731 0.80 ALDH1A1 (0.31) ALDH1A1
SCHEMBL15863275 0.80 SMARCA2 (0.35) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
SCHEMBL7730997 0.80 SMARCA2 (0.35) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
SCHEMBL7734542 0.79 ALDH1A1 (0.35) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL15863273 0.79 SMARCA2 (0.36) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E
Hydrochloric Acid SCHEMBL15863271 0.79 SMARCA2 (0.36) SMARCA2PBRM1ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2240520-B1 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC (US) 2019-04-24 EP disclosed
EP-2240520-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS ExxonMobil Chemical Patents Inc. (US) 2010-10-20 EP disclosed
US-7812104-B2 Production of propylene-based polymers EXXONMOBIL CHEMICAL PATENTS INC. (US) 2010-10-12 US disclosed
EP-2103634-A1 Production of propylene-based polymers ExxonMobil Chemical Patents Inc. (US) 2009-09-23 EP disclosed
US-20090186995-A1 Production of Propylene-Based Polymers EXXONMOBIL CHEMICAL PATENTS INC. 2009-07-23 US disclosed
WO-2009091480-A2 PRODUCTION OF PROPYLENE-BASED POLYMERS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2009-07-23 WO disclosed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed
US-6635733-B2 Coordination catalyst; radiation transparent, elasticity CHISSO CORPORATION (JP) 2003-10-21 US disclosed
US-6479646-B1 Metallocene compounds having indenyl ligand and catalysts for olefin polymerization containing the same CHISSO CORPORATION (JP) 2002-11-12 US disclosed
US-20020002261-A1 Elastomeric polypropylene JNC PETROCHEMICAL CORPORATION (JP) 2002-01-03 US disclosed
US-20010031834-A1 Using coordination catalyst; flexibility, elasticity; molding materials CHISSO CORPORATION 2001-10-18 US disclosed